Tare da shekaru, asarar peptide, karfin bango na bango na jini yana raguwa, yana rinjayar kwanciyar hankali na karfin jini, danko na jini, mai sauƙi don haifar da hanta mai kitse, hyperlipidemia, thrombosis na kwakwalwa, da ƙwaƙwalwar ƙwaƙwalwar ajiya, dizziness, mantuwa, rashin barci.Rashin peptides na iya haifar da raguwar yawan kashi, samuwar cavities, da asarar calcium, haifar da kashi da ciwon haɗin gwiwa, ƙwayar kashi, ƙafafu da ƙafafu marasa sassauƙa, osteoporosis, raguwa mai sauƙi, jinkirin warkar da kashi, da rage taurin kashi.